diff --git a/gulpfile.js b/gulpfile.js
index c7863c075..4d574269f 100644
--- a/gulpfile.js
+++ b/gulpfile.js
@@ -80,7 +80,7 @@ const ENV_TARGETS = [
   "Chrome >= 88",
   "Firefox ESR",
   "Safari >= 14.1",
-  "Node >= 16",
+  "Node >= 18",
   "> 1%",
   "not IE > 0",
   "not dead",
@@ -2168,7 +2168,6 @@ function packageJson() {
     },
     dependencies: {
       "path2d-polyfill": "^2.0.1",
-      "web-streams-polyfill": "^3.2.1",
     },
     browser: {
       canvas: false,
@@ -2184,7 +2183,7 @@ function packageJson() {
       url: DIST_REPO_URL,
     },
     engines: {
-      node: ">=16",
+      node: ">=18",
     },
   };
 
diff --git a/package-lock.json b/package-lock.json
index 1feb190a2..1c5469733 100644
--- a/package-lock.json
+++ b/package-lock.json
@@ -62,14 +62,13 @@
         "typogr": "^0.6.8",
         "vinyl": "^3.0.0",
         "vinyl-fs": "^3.0.3",
-        "web-streams-polyfill": "^3.2.1",
         "webpack": "^5.80.0",
         "webpack-stream": "^7.0.0",
         "wintersmith": "^2.5.0",
         "yargs": "^17.7.1"
       },
       "engines": {
-        "node": ">=16"
+        "node": ">=18"
       }
     },
     "node_modules/@ampproject/remapping": {
@@ -18622,15 +18621,6 @@
         "node": ">=10.13.0"
       }
     },
-    "node_modules/web-streams-polyfill": {
-      "version": "3.2.1",
-      "resolved": "https://registry.npmjs.org/web-streams-polyfill/-/web-streams-polyfill-3.2.1.tgz",
-      "integrity": "sha512-e0MO3wdXWKrLbL0DgGnUV7WHVuw9OUvL4hjgnPkIeEvESk74gAITi5G606JtZPp39cd8HA9VQzCIvA49LpPN5Q==",
-      "dev": true,
-      "engines": {
-        "node": ">= 8"
-      }
-    },
     "node_modules/webidl-conversions": {
       "version": "3.0.1",
       "resolved": "https://registry.npmjs.org/webidl-conversions/-/webidl-conversions-3.0.1.tgz",
@@ -33566,12 +33556,6 @@
         "graceful-fs": "^4.1.2"
       }
     },
-    "web-streams-polyfill": {
-      "version": "3.2.1",
-      "resolved": "https://registry.npmjs.org/web-streams-polyfill/-/web-streams-polyfill-3.2.1.tgz",
-      "integrity": "sha512-e0MO3wdXWKrLbL0DgGnUV7WHVuw9OUvL4hjgnPkIeEvESk74gAITi5G606JtZPp39cd8HA9VQzCIvA49LpPN5Q==",
-      "dev": true
-    },
     "webidl-conversions": {
       "version": "3.0.1",
       "resolved": "https://registry.npmjs.org/webidl-conversions/-/webidl-conversions-3.0.1.tgz",
diff --git a/package.json b/package.json
index cdb42c66f..c3fd6999d 100644
--- a/package.json
+++ b/package.json
@@ -55,7 +55,6 @@
     "typogr": "^0.6.8",
     "vinyl": "^3.0.0",
     "vinyl-fs": "^3.0.3",
-    "web-streams-polyfill": "^3.2.1",
     "webpack": "^5.80.0",
     "webpack-stream": "^7.0.0",
     "wintersmith": "^2.5.0",
@@ -69,7 +68,7 @@
     "url": "git://github.com/mozilla/pdf.js.git"
   },
   "engines": {
-    "node": ">=16"
+    "node": ">=18"
   },
   "license": "Apache-2.0"
 }
diff --git a/src/core/worker.js b/src/core/worker.js
index 14f5a576a..b5b2f5059 100644
--- a/src/core/worker.js
+++ b/src/core/worker.js
@@ -133,14 +133,10 @@ class WorkerMessageHandler {
       // Ensure that (primarily) Node.js users won't accidentally attempt to use
       // a non-translated/non-polyfilled build of the library, since that would
       // quickly fail anyway because of missing functionality.
-      if (
-        (isNodeJS && typeof Path2D === "undefined") ||
-        typeof ReadableStream === "undefined"
-      ) {
+      if (isNodeJS && typeof Path2D === "undefined") {
         const partialMsg =
           "The browser/environment lacks native support for critical " +
-          "functionality used by the PDF.js library " +
-          "(e.g. `Path2D` and/or `ReadableStream`); ";
+          "functionality used by the PDF.js library (e.g. `Path2D`); ";
 
         if (isNodeJS) {
           throw new Error(partialMsg + "please use a `legacy`-build instead.");
diff --git a/src/shared/compatibility.js b/src/shared/compatibility.js
index 8375e62a7..35a42ab4b 100644
--- a/src/shared/compatibility.js
+++ b/src/shared/compatibility.js
@@ -36,17 +36,7 @@ import { isNodeJS } from "./is_node.js";
   polyfillPath2D(globalThis);
 })();
 
-// Support: Node.js<18.0.0
-(function checkReadableStream() {
-  if (globalThis.ReadableStream || !isNodeJS) {
-    return;
-  }
-  globalThis.ReadableStream = __non_webpack_require__(
-    "web-streams-polyfill/dist/ponyfill.js"
-  ).ReadableStream;
-})();
-
-// Support: Firefox<90, Chrome<92, Safari<15.4, Node.js<16.6.0
+// Support: Chrome<92, Safari<15.4
 (function checkArrayAt() {
   if (Array.prototype.at) {
     return;
@@ -54,7 +44,7 @@ import { isNodeJS } from "./is_node.js";
   require("core-js/es/array/at.js");
 })();
 
-// Support: Firefox<90, Chrome<92, Safari<15.4, Node.js<16.6.0
+// Support: Chrome<92, Safari<15.4
 (function checkTypedArrayAt() {
   if (Uint8Array.prototype.at) {
     return;
@@ -62,7 +52,7 @@ import { isNodeJS } from "./is_node.js";
   require("core-js/es/typed-array/at.js");
 })();
 
-// Support: Firefox<94, Chrome<98, Safari<15.4, Node.js<17.0.0
+// Support: Chrome<98, Safari<15.4
 (function checkStructuredClone() {
   if (typeof PDFJSDev !== "undefined" && PDFJSDev.test("IMAGE_DECODERS")) {
     // The current image decoders are synchronous, hence `structuredClone`