diff --git a/.github/workflows/ci.yml b/.github/workflows/ci.yml
index 6cc016009..924c6d81c 100644
--- a/.github/workflows/ci.yml
+++ b/.github/workflows/ci.yml
@@ -9,8 +9,9 @@ jobs:
     runs-on: ubuntu-latest
 
     strategy:
+      fail-fast: false
       matrix:
-        node-version: [18, lts/*]
+        node-version: [18, lts/*, latest]
 
     steps:
       - name: Checkout repository
diff --git a/test/unit/annotation_spec.js b/test/unit/annotation_spec.js
index 6791d8419..4b421d2ee 100644
--- a/test/unit/annotation_spec.js
+++ b/test/unit/annotation_spec.js
@@ -26,6 +26,7 @@ import {
   AnnotationFieldFlag,
   AnnotationFlag,
   AnnotationType,
+  isNodeJS,
   OPS,
   RenderingIntentFlag,
   stringToBytes,
@@ -34,6 +35,7 @@ import {
 import {
   CMAP_URL,
   createIdFactory,
+  getNodeVersion,
   STANDARD_FONT_DATA_URL,
   XRefMock,
 } from "./test_utils.js";
@@ -2207,6 +2209,12 @@ describe("annotation", function () {
     });
 
     it("should compress and save text", async function () {
+      if (isNodeJS && getNodeVersion().major === 21) {
+        pending(
+          "CompressionStream behaves differently in Node.js 21, " +
+            "compared to Firefox, Chrome, and Node.js 18/20."
+        );
+      }
       const textWidgetRef = Ref.get(123, 0);
       const xref = new XRefMock([
         { ref: textWidgetRef, data: textWidgetDict },
diff --git a/test/unit/test_utils.js b/test/unit/test_utils.js
index 111c05006..7dcdc5542 100644
--- a/test/unit/test_utils.js
+++ b/test/unit/test_utils.js
@@ -144,11 +144,22 @@ function createIdFactory(pageIndex) {
   return page._localIdFactory;
 }
 
+function getNodeVersion() {
+  if (!isNodeJS) {
+    throw new Error("getNodeVersion - only valid in Node.js environments.");
+  }
+  const [major, minor, patch] = process.versions.node
+    .split(".")
+    .map(parseFloat);
+  return { major, minor, patch };
+}
+
 export {
   buildGetDocumentParams,
   CMAP_URL,
   createIdFactory,
   DefaultFileReaderFactory,
+  getNodeVersion,
   STANDARD_FONT_DATA_URL,
   TEST_PDFS_PATH,
   XRefMock,